Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377604 | 0.81 | HDAC1 (0.46) | HSD17B10TSHRLMNASMN1; SMN2DPP4 | |
| SCHEMBL3891473 | 0.78 | HSD17B10 (0.75) | HSD17B10TSHRLMNAALOX15SMN1; SMN2 | |
| SCHEMBL11424184 | 0.78 | DPP4 (0.61) | TSHRSMN1; SMN2DPP4MAPTNPC1 | |
| SCHEMBL11430656 | 0.70 | GAA (0.50) | GAANPC1 | |
| SCHEMBL11382463 | 0.70 | ALDH1A1 (0.45) | TSHRDPP4DPP8DPP9ALDH1A1 | |
| SCHEMBL28159525 | 0.70 | GAA (0.57) | HSD17B10TSHRLMNAALOX15SMN1; SMN2 | |
| SCHEMBL13753536 | 0.70 | TSHR (0.68) | HSD17B10TSHRLMNAALOX15SMN1; SMN2 | |
| SCHEMBL28846715 | 0.70 | GAA (0.57) | HSD17B10TSHRLMNAALOX15SMN1; SMN2 | |
| SCHEMBL11380401 | 0.70 | CHRNA7 (0.51) | TSHRLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11375664 | 0.70 | HPGD (0.49) | SMN1; SMN2DPP4DPP8DPP9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |