Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376801 | 0.81 | DPP4 (0.55) | PREP | |
| SCHEMBL11391611 | 0.81 | PREP (0.48) | GAAPREP | |
| SCHEMBL11382988 | 0.81 | PREP (0.51) | GAAPREPKDM4E | |
| SCHEMBL11375664 | 0.79 | HPGD (0.49) | PREPPOLB | |
| SCHEMBL11375517 | 0.78 | PREP (0.48) | GAANPC1PREPKDM4E | |
| SCHEMBL11387722 | 0.78 | CHRNB2 (0.50) | GAACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11381022 | 0.76 | CA2 (0.52) | PREP | |
| SCHEMBL11430662 | 0.76 | PREP (0.73) | PREP | |
| SCHEMBL11384465 | 0.75 | PREP (0.58) | GAANPC1PREP | |
| SCHEMBL11382443 | 0.74 | L3MBTL1 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |