Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378388 | 0.81 | HSD17B10 (0.54) | DPP4ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11424184 | 0.80 | DPP4 (0.61) | DPP4SMN1; SMN2TSHRRAB9ANPC1 | |
| SCHEMBL11373157 | 0.78 | PREP (0.49) | DPP4RAB9ANPC1 | |
| SCHEMBL11376777 | 0.74 | PPIA (0.48) | DPP4DPP8DPP9 | |
| SCHEMBL11390362 | 0.74 | PREP (0.45) | DPP4KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL11375598 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KMT2ALMNAHSD17B10RAB9A | |
| SCHEMBL11372875 | 0.74 | CTSL (0.49) | ALDH1A1KMT2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL11369166 | 0.74 | HCAR2 (0.41) | HDAC1DPP4DPP8DPP9 | |
| SCHEMBL11412004 | 0.73 | CTSB (0.47) | DPP4KMT2ARAB9ANPC1CYP2D6 | |
| SCHEMBL11369671 | 0.73 | KMT2A (0.50) | DPP4ALDH1A1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |