Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383035 | 0.96 | S1PR1 (0.33) | KDRRIPK1CNR2 | |
| SCHEMBL11374129 | 0.88 | KDR (0.35) | KDR | |
| SCHEMBL11381338 | 0.87 | KDR (0.36) | KDR | |
| SCHEMBL11384600 | 0.86 | KDR (0.32) | KDRRIPK1 | |
| SCHEMBL11375232 | 0.82 | RIPK1 (0.31) | RIPK1CNR2 | |
| SCHEMBL11376572 | 0.81 | KDR (0.34) | KDR | |
| SCHEMBL11596461 | 0.78 | — | — | |
| SCHEMBL11387518 | 0.77 | RAB9A (0.49) | RIPK1 | |
| SCHEMBL11491168 | 0.77 | RIPK1 (0.36) | RIPK1 | |
| SCHEMBL11385079 | 0.74 | PTPN1 (0.34) | KDRCNR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243674-A | HYPOTENSIVE AGENTS; ANALGESICS; ANTISECRETORY AGENTS; ANTIBODY INHIBITORS, AND TRANQUILIZERS | PFIZER INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4143139-A | ANALGESICS, HYPOTENSIVES, IMMUNOSUPPRESSANTS, TRANQUILIZERS, ANTISECRETORY, ANTI-ANXIETY | PFIZER INC. (US) | 1979-03-06 | — | — | US | disclosed |