Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.52 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649682 | 0.80 | PDE4B (0.69) | PDE4BSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL4115394 | 0.77 | SIGMAR1 (0.72) | PDE4BSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL26125846 | 0.72 | POLB (0.56) | PDE4BSMN1; SMN2ALDH1A1HRH3POLB | |
| SCHEMBL1138033 | 0.72 | PDE4B (0.53) | PDE4BSMN1; SMN2ALDH1A1HPGDMEN1 | |
| Ammonia Solution, Strong SCHEMBL2931430 | 0.71 | SIGMAR1 (0.58) | PDE4BSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL2928330 | 0.69 | SMN1; SMN2 (0.64) | PDE4BSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL11196105 | 0.69 | NCF1 (0.83) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| 4-(4-Chlorobenzyl)Morpholine SCHEMBL4103722 | 0.69 | HRH3 (0.74) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL16281858 | 0.68 | AXL (0.55) | PDE4BALDH1A1MAPTNCF1SIGMAR1 | |
| SCHEMBL30417288 | 0.68 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HPGDMEN1PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765358-B1 | TREATMENT OR PREVENTION OF SKIN CONDITIONS OR TISSUE CONDITIONS IN ANIMALS USING BORYLOXYPYRIDYLMETHANONES | ANACOR PHARMACEUTICALS INC (US) | 2011-02-23 | — | — | EP | disclosed |
| EP-1765358-A2 | TREATMENT OR PREVENTION OF SKIN CONDITIONS OR TISSUE CONDITIONS IN ANIMALS USING BORYLOXYPYRIDYLMETHANONES | Anacor Pharmaceuticals, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123094-A2 | TREATMENT OR PREVENTION OF SKIN CONDITIONS OR TISSUE CONDITIONS IN ANIMALS USING BORYLOXYPYRIDYLMETHANONES | ANACOR PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |