Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.52 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28074495 | 0.80 | CHUK (0.56) | PDE4BSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1138032 | 0.80 | PDE4B (0.65) | PDE4BSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL4115394 | 0.79 | SIGMAR1 (0.72) | PDE4BSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL14872333 | 0.77 | HRH3 (0.59) | SMN1; SMN2HPGDMEN1KMT2AHRH3 | |
| SCHEMBL4465612 | 0.76 | HRH3 (0.59) | PDE4BSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL13161945 | 0.76 | HRH3 (0.62) | SMN1; SMN2HPGDMEN1KMT2AHRH3 | |
| SCHEMBL18520383 | 0.76 | PDE4B (0.52) | PDE4BSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL16281858 | 0.76 | AXL (0.55) | PDE4BALDH1A1NCF1SIGMAR1TNKS | |
| SCHEMBL16883444 | 0.75 | HRH3 (0.59) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28830139 | 0.74 | CHUK (0.59) | HRH3TNKSJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |