Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11395925 | 0.88 | OPRL1 (0.71) | OPRL1OPRM1 | |
| SCHEMBL7885693 | 0.84 | OPRL1 (0.65) | OPRL1ADRB2ADRB1ADRB3 | |
| SCHEMBL4805093 | 0.82 | OPRL1 (0.69) | OPRL1ADRB2OPRM1ADRB1ADRB3 | |
| SCHEMBL11647483 | 0.79 | CHRM1 (0.69) | OPRL1ADRB2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5984390 | 0.79 | OPRL1 (0.75) | OPRL1ADRB2ALDH1A1OPRM1ADRB1 | |
| SCHEMBL14571570 | 0.78 | OPRL1 (0.59) | OPRL1ADRB2OPRM1ADRB1ADRB3 | |
| SCHEMBL4802544 | 0.78 | OPRL1 (0.66) | OPRL1ADRB2ALDH1A1OPRM1ADRB1 | |
| SCHEMBL11651024 | 0.78 | OPRL1 (1.00) | OPRL1OPRM1ADRA1DADRA1AADRA1B | |
| SCHEMBL4812163 | 0.78 | OPRL1 (0.66) | OPRL1ADRB2ALDH1A1OPRM1ADRB1 | |
| Hydrochloric Acid SCHEMBL4798788 | 0.77 | OPRL1 (0.65) | OPRL1ADRB2ALDH1A1OPRM1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304915-A | ADRENERGIC BLOCKING AGENTS, HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | SANDOZ LTD. (CH) | 1981-12-08 | — | — | US | claimed |
| US-4304915-A | ADRENERGIC BLOCKING AGENTS, HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | SANDOZ LTD. (CH) | 1981-12-08 | — | — | US | disclosed |