Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 17/20 | 0.75 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.61 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651021 | 0.86 | OPRL1 (0.76) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL11648914 | 0.86 | OPRL1 (0.75) | OPRL1OPRM1CHRM1DRD2DRD3 | |
| SCHEMBL11395925 | 0.83 | OPRL1 (0.71) | OPRL1OPRM1 | |
| SCHEMBL4805093 | 0.82 | OPRL1 (0.69) | OPRL1OPRM1CHRM2CHRM1DRD2 | |
| SCHEMBL4807271 | 0.80 | OPRL1 (0.67) | OPRL1OPRM1 | |
| SCHEMBL11644820 | 0.80 | OPRM1 (0.67) | OPRL1OPRM1CHRM1DRD2DRD4 | |
| SCHEMBL5984390 | 0.80 | OPRL1 (0.75) | OPRL1OPRM1CHRM1DRD2ADRA1D | |
| SCHEMBL4812163 | 0.79 | OPRL1 (0.66) | OPRL1OPRM1ADRA1DADRA1AADRA1B | |
| SCHEMBL4802544 | 0.79 | OPRL1 (0.66) | OPRL1OPRM1CHRM1DRD2ADRA1D | |
| SCHEMBL7885693 | 0.79 | OPRL1 (0.65) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080328-A | N-substituted heterocyclic derivatives and preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-03-21 | — | — | US | disclosed |