Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | OGG1 | O15527 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386262 | 0.98 | ERCC5 (0.44) | ERCC5FEN1MAPTALDH1A1KDM4E | |
| SCHEMBL11384431 | 0.93 | ERCC5 (0.45) | ERCC5FEN1MAPTALDH1A1KDM4E | |
| SCHEMBL11387906 | 0.84 | TAS1R3 (0.38) | ERCC5FEN1MAPTALDH1A1KDM4E | |
| SCHEMBL11375267 | 0.82 | CTSD (0.50) | MAPTALDH1A1CTSDCA1CA2 | |
| SCHEMBL11382113 | 0.79 | ALDH1A1 (0.44) | ERCC5FEN1MAPTALDH1A1KDM4E | |
| SCHEMBL4384455 | 0.78 | TAS1R3 (0.60) | ERCC5FEN1MAPTALDH1A1KDM4E | |
| SCHEMBL11377884 | 0.77 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4EOGG1CTSD | |
| SCHEMBL2664419 | 0.77 | MAPT (0.49) | MAPTALDH1A1KDM4ECTSDCA1 | |
| SCHEMBL11383781 | 0.76 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EOGG1CTSD | |
| SCHEMBL29746220 | 0.75 | CA1 (0.47) | MAPTALDH1A1KDM4EOGG1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247474-A | POLYFUNCTIONAL ALKYLENE, CYCLOALKYLENE, OR ARYLENE DERIVATIVES; HYDROGEN CHLORIDE SALTS USED AS CURING AGENTS | HERCULES INCORPORATED (US) | 1981-01-27 | — | — | US | disclosed |