Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14204147 | 0.87 | NOTUM (0.43) | SMN1; SMN2TSHRLMNAHSD17B10HPGD | |
| SCHEMBL11419391 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2LMNAHSD17B10HPGDPARP1 | |
| SCHEMBL7805983 | 0.75 | KDM4E (0.43) | SMN1; SMN2TSHRLMNAHSD17B10HPGD | |
| SCHEMBL6565290 | 0.75 | KDM4E (0.43) | SMN1; SMN2TSHRLMNAHSD17B10HPGD | |
| SCHEMBL14160787 | 0.74 | KDM4E (0.50) | SMN1; SMN2TSHRLMNAHPGDGSK3A | |
| SCHEMBL5012601 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRLMNAGSK3AGSK3B | |
| SCHEMBL10480363 | 0.71 | KDM4E (0.51) | SMN1; SMN2TSHRLMNAKDM4ENPSR1 | |
| SCHEMBL4784826 | 0.71 | CYP2C19 (0.57) | SMN1; SMN2TSHRLMNAHSD17B10KDM4E | |
| SCHEMBL1104400 | 0.70 | ALDH1A1 (0.50) | SMN1; SMN2TSHRLMNAHPGDKDM4E | |
| SCHEMBL10012854 | 0.70 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRLMNAHPGDGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271308-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4120864-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-10-17 | — | — | US | disclosed |