Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | PNP | P00491 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175302 | 0.86 | KDM4E (0.50) | KDM4ETSHRNPSR1CYP19A1PNP | |
| SCHEMBL14160787 | 0.81 | KDM4E (0.50) | KDM4ETSHRNPSR1CYP19A1ALDH1A1 | |
| SCHEMBL7805983 | 0.78 | KDM4E (0.43) | KDM4ETSHRNPSR1CYP19A1ALDH1A1 | |
| SCHEMBL10480363 | 0.78 | KDM4E (0.51) | KDM4ETSHRNPSR1CYP19A1ALDH1A1 | |
| SCHEMBL10012854 | 0.76 | SMN1; SMN2 (0.52) | KDM4ETSHRNPSR1CYP19A1ALDH1A1 | |
| SCHEMBL1104400 | 0.76 | ALDH1A1 (0.50) | KDM4ETSHRNPSR1ALDH1A1HPGD | |
| SCHEMBL10480359 | 0.76 | ALDH1A1 (0.51) | KDM4ETSHRNPSR1CYP19A1ALDH1A1 | |
| SCHEMBL5012601 | 0.75 | SMN1; SMN2 (0.41) | KDM4ETSHRNPSR1CYP19A1ALDH1A1 | |
| SCHEMBL15801095 | 0.75 | KDM4E (0.45) | KDM4ETSHRNPSR1CYP19A1ALDH1A1 | |
| SCHEMBL11380650 | 0.75 | SMN1; SMN2 (0.41) | KDM4ETSHRNPSR1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809144-B1 | Substantially non-photosensitive thermographic recording material with improved stability and image-tone | AGFA GEVAERT (BE) | 2004-04-07 | — | — | EP | disclosed |
| US-5854174-A | Substantially non-photosensitive thermographic recording material with improved stability and image-tone | AGFA-GEVAERT (BE) | 1998-12-29 | — | — | US | disclosed |
| US-5750319-A | LIGHT-INSENSITIVE ORGANIC SILVER SALT, ORGANIC REDUCING AGENT, 1,2,4-TRIAZOLE COMPOUND | AGFA-GEVAERT (BE) | 1998-05-12 | — | — | US | disclosed |
| EP-0809144-A1 | Substantially non-photosensitive thermographic recording material with improved stability and image-tone | AGFA-GEVAERT N.V. (BE) | 1997-11-26 | — | — | EP | disclosed |
| EP-0809143-A1 | Substantially non-photosensitive thermographic recording material with improved stability and image-tone | AGFA-GEVAERT N.V. (BE) | 1997-11-26 | — | — | EP | disclosed |