Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | CCR4 | P51679 | 1/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383329 | 0.93 | RAD52 (0.61) | RAD52L3MBTL1FGFR1SRCMCHR1 | |
| SCHEMBL11384862 | 0.90 | XDH (0.57) | L3MBTL1MCHR1BCHEACHELTA4H | |
| SCHEMBL1796429 | 0.83 | MAOB (0.56) | KDM4EBCHEACHEMAOBXDH | |
| SCHEMBL1792736 | 0.83 | MAOB (0.53) | MCHR1BCHEACHEMAOBXDH | |
| SCHEMBL11387442 | 0.82 | XDH (0.54) | L3MBTL1MCHR1BCHEACHELTA4H | |
| SCHEMBL1793217 | 0.82 | MAOB (0.58) | MAOBXDH | |
| SCHEMBL11390075 | 0.81 | XDH (0.56) | RAD52L3MBTL1KDM4EALDH1A1LTA4H | |
| SCHEMBL11389372 | 0.81 | HRH3 (0.55) | MCHR1BCHEACHEMAOBXDH | |
| SCHEMBL1794312 | 0.81 | SIGMAR1 (0.49) | BCHEACHEMAOBXDH | |
| SCHEMBL1795459 | 0.81 | SIGMAR1 (0.52) | BCHEACHEMAOBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4244954-A | Acridine compounds and methods of combatting viruses with them | STERLING DRUG INC. (US) | 1981-01-13 | — | — | US | disclosed |