Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445083 | 0.87 | BRD4 (0.37) | SLC6A3CHRM2CHRM4CHRM3ALDH1A1 | |
| SCHEMBL2125458 | 0.87 | BRD4 (0.37) | SLC6A3CHRM2CHRM4CHRM3ALDH1A1 | |
| SCHEMBL30444800 | 0.87 | BRD4 (0.37) | SLC6A3CHRM2CHRM4CHRM3ALDH1A1 | |
| SCHEMBL19807408 | 0.72 | SLC6A3 (0.42) | SLC6A3ALDH1A1SLC6A4BRD4 | |
| SCHEMBL6765079 | 0.72 | SLC6A3 (0.42) | SLC6A3ALDH1A1SLC6A4BRD4 | |
| SCHEMBL19713548 | 0.70 | CHRM2 (0.40) | SLC6A3CHRM2CHRM4CHRM3SLC6A4 | |
| SCHEMBL10979763 | 0.70 | CHRM2 (0.40) | SLC6A3CHRM2CHRM4CHRM3SLC6A4 | |
| SCHEMBL22006161 | 0.70 | CHRM2 (0.40) | SLC6A3CHRM2CHRM4CHRM3SLC6A4 | |
| SCHEMBL17803325 | 0.70 | CHRM2 (0.40) | SLC6A3CHRM2CHRM4CHRM3SLC6A4 | |
| SCHEMBL9967101 | 0.70 | CHRM2 (0.42) | SLC6A3CHRM2CHRM4CHRM3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304772-A | Ethanocarbazole derivatives and antidepressant compositions | AYERST, MCKENNA & HARRISON, INC. (CA) | 1981-12-08 | — | — | US | disclosed |