Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807408 | 1.00 | SLC6A3 (0.42) | SLC6A3CYP1A2HIF1AALDH1A1SLC6A4 | |
| SCHEMBL19229897 | 0.82 | EPHX2 (0.43) | CYP1A2ALDH1A1POLBMEN1CYP2C9 | |
| SCHEMBL854658 | 0.73 | TLR4 (0.39) | CYP1A2ALDH1A1POLBMEN1CYP2C9 | |
| SCHEMBL11384348 | 0.72 | SLC6A3 (0.36) | SLC6A3ALDH1A1SLC6A4BRD4 | |
| SCHEMBL7419212 | 0.71 | CYP1A2 (0.45) | SLC6A3CYP1A2HIF1AALDH1A1BRD4 | |
| SCHEMBL18527521 | 0.71 | CYP1A2 (0.45) | SLC6A3CYP1A2HIF1AALDH1A1BRD4 | |
| SCHEMBL9730177 | 0.71 | ALDH1A1 (0.46) | CYP1A2HIF1AALDH1A1BRD4KMT2A | |
| SCHEMBL706994 | 0.69 | CHRNB2 (0.39) | SLC6A3CYP1A2HIF1AALDH1A1BRD4 | |
| SCHEMBL5897591 | 0.69 | CYP1A2 (0.39) | CYP1A2HIF1AALDH1A1BRD4POLB | |
| SCHEMBL1874741 | 0.69 | CYP1A2 (0.39) | CYP1A2HIF1AALDH1A1BRD4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493744-B1 | Tropane analogs and methods for inhibition of monoamine transport | ORGANIX INC (US) | 2009-11-25 | — | — | EP | disclosed |
| US-6677338-B2 | FOR THERAPY OF DEPRESSION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2004-01-13 | — | — | US | disclosed |
| US-20030105096-A1 | Serotonin transport inhibitors | WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105096-A1 | Serotonin transport inhibitors | SLC6A4, SLC6A2, SLC18A2 | SLC6A3 4/4885CYP1A2 600/4885HIF1A 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.