Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 10/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380779 | 0.95 | PDE5A (0.45) | PDE5ACBFBNPC1TP53POLB | |
| SCHEMBL11375759 | 0.92 | GUSB (0.50) | PDE5ACBFBNPC1TP53POLB | |
| SCHEMBL11387133 | 0.87 | CBFB (0.53) | CBFBPOLBGUSBPDE4APDE4B | |
| SCHEMBL11383679 | 0.85 | PDE5A (0.66) | PDE5AMAPTGUSBPDE4APDE4B | |
| SCHEMBL11377954 | 0.84 | CBFB (0.41) | PDE5ACBFBNPC1TP53POLB | |
| SCHEMBL11380722 | 0.80 | PDE5A (0.59) | PDE5ANPC1TP53POLBMAPT | |
| SCHEMBL11381930 | 0.80 | ALDH1A1 (0.55) | CBFBNPC1TP53POLBMAPT | |
| SCHEMBL11375259 | 0.80 | PDE5A (0.58) | PDE5AMAPTGUSBPDE4APDE4B | |
| SCHEMBL11374673 | 0.77 | GUSB (0.58) | PDE5ANPC1TP53POLBMAPT | |
| SCHEMBL11384695 | 0.77 | GUSB (0.71) | PDE5ANPC1TP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |