Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382091 | 0.83 | OPRK1 (0.49) | OPRM1OPRD1OPRK1CHRM1HRH1 | |
| SCHEMBL11379114 | 0.81 | OPRD1 (0.47) | OPRM1OPRD1OPRK1CHRM1HRH1 | |
| SCHEMBL11382034 | 0.78 | OPRK1 (0.50) | OPRM1OPRD1OPRK1CHRM1HRH1 | |
| Hydrochloric Acid SCHEMBL11380464 | 0.78 | OPRK1 (0.49) | OPRM1OPRD1OPRK1CHRM1HRH1 | |
| SCHEMBL11376047 | 0.73 | CYP2J2 (0.58) | HRH1DRD2KCNH2 | |
| SCHEMBL11371371 | 0.72 | OPRK1 (0.53) | OPRM1OPRD1OPRK1CHRM1HRH1 | |
| SCHEMBL11543696 | 0.72 | CYP2J2 (0.63) | OPRM1OPRD1OPRK1CHRM1HRH1 | |
| SCHEMBL11374333 | 0.71 | OPRD1 (0.52) | OPRM1OPRD1OPRK1CHRM1HRH1 | |
| Hydrochloric Acid SCHEMBL11833697 | 0.71 | CYP2J2 (0.62) | OPRM1OPRD1OPRK1CHRM1HRH1 | |
| Hydrochloric Acid SCHEMBL11828383 | 0.71 | CYP2J2 (0.62) | OPRM1OPRD1OPRK1CHRM1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285958-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4254130-A | ANTIALLERGENS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |