Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.52 |
| ▸ | MCOLN2 | Q8IZK6 | 6/20 | 0.50 |
| ▸ | MCOLN1 | Q9GZU1 | 6/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387313 | 0.86 | SLC18A3 (0.54) | SLC18A3ALDH1A1LMNATSHRADRA1D | |
| SCHEMBL11393336 | 0.81 | SLC18A3 (0.50) | SLC18A3MCOLN2MCOLN1MCOLN3LMNA | |
| SCHEMBL11396476 | 0.81 | SLC18A3 (0.55) | SLC18A3ALDH1A1CRHBPCRHR2LMNA | |
| SCHEMBL11395690 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNARAB9AKDM4E | |
| SCHEMBL11393149 | 0.77 | CRHBP (0.40) | SLC18A3ALDH1A1CRHBPCRHR2 | |
| SCHEMBL11385218 | 0.76 | ADRA1A (0.36) | MCOLN2MCOLN1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL11161118 | 0.75 | ADRA1A (0.35) | MCOLN2MCOLN1ADRA1DADRA1AADRA1B | |
| SCHEMBL11394248 | 0.74 | CRHBP (0.40) | SLC18A3ALDH1A1CRHBPCRHR2LMNA | |
| SCHEMBL13698537 | 0.74 | SLC18A3 (0.65) | SLC18A3MCOLN2MCOLN1MCOLN3ALDH1A1 | |
| SCHEMBL11162863 | 0.73 | ADRA1A (0.34) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258188-A | HYPOTENSIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-03-24 | — | — | US | claimed |