Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372144 | 0.86 | KDM4E (0.65) | TBXAS1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7877546 | 0.80 | MAPT (0.73) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL13408067 | 0.77 | TBXAS1 (0.56) | TBXAS1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7114988 | 0.75 | MAPT (0.51) | TBXAS1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7114985 | 0.75 | MAPT (0.51) | TBXAS1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL8253461 | 0.74 | CHRNB2 (0.56) | TBXAS1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7749049 | 0.73 | TBXAS1 (0.52) | TBXAS1KDM4EALDH1A1MAPTMTNR1A | |
| SCHEMBL11348399 | 0.73 | MAPT (0.65) | TBXAS1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL11965205 | 0.73 | TBXAS1 (0.52) | TBXAS1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6216616 | 0.73 | CHRNB2 (0.55) | TBXAS1KDM4EALDH1A1MAPTKLK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0020391-A1 | SUBSTITUTED ACETIC ACID ESTERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-01-07 | — | — | EP | disclosed |
| WO-1980000563-A1 | SUBSTITUTED ACETIC ACID ESTERS | SOREX LTD (GB) | 1980-04-03 | — | — | WO | disclosed |