Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14166261 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL12933666 | 0.96 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL27950338 | 0.95 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL8633351 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL27452158 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL8844957 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL27390202 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL18918539 | 0.83 | MAOA (0.47) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL19610339 | 0.82 | HDAC3 (0.44) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL14166030 | 0.82 | MAOA (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256464-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2022-05-11 | — | — | EP | disclosed |
| US-4287335-A | WHEREIN SAID COMPOUND IS A STYRYLPYRIDINIUM SALT OR A STYRYLQUINOLINIUM SALT USEFUL IN PRODUCING A PHOTOSENSITIVE RESIN | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1981-09-01 | — | — | US | disclosed |