Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.55 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752591 | 0.74 | ALDH1A1 (0.47) | RAD52ALDH1A1CYP3A4SMN1; SMN2CYP1A2 | |
| SCHEMBL9076137 | 0.74 | CHEK1 (0.44) | CHEK1LIMK1CES1TGM2AHR | |
| SCHEMBL11348054 | 0.73 | TGM2 (0.39) | CES1TGM2RAD52 | |
| SCHEMBL23061562 | 0.73 | TGM2 (0.39) | CES1TGM2RAD52AHRCMA1 | |
| SCHEMBL15621888 | 0.73 | RAD52 (0.43) | CHEK1RAD52ALDH1A1CYP3A4TSHR | |
| SCHEMBL4786389 | 0.72 | CHEK1 (0.50) | CHEK1LIMK1CES1TGM2AHR | |
| SCHEMBL13868943 | 0.72 | CHEK1 (0.59) | CHEK1LIMK1CES1TGM2AHR | |
| SCHEMBL13868946 | 0.72 | CHEK1 (0.59) | CHEK1LIMK1CES1TGM2AHR | |
| Fluoride SCHEMBL3292595 | 0.70 | — | — | |
| SCHEMBL3642313 | 0.69 | RAD52 (0.61) | RAD52NOX1BCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256901-A | Phthalone derivatives utilizable as pigments | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1981-03-17 | — | — | US | disclosed |