Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209666 | 0.77 | KMT2A (0.42) | KDM4EALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL28512693 | 0.72 | TSHR (0.51) | KDM4EALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL4679065 | 0.71 | HPGD (0.53) | KDM4EALDH1A1TSHRL3MBTL1LMNA | |
| SCHEMBL18551961 | 0.71 | ATM (0.46) | ALDH1A1TSHRTDP1L3MBTL1LMNA | |
| SCHEMBL28366032 | 0.70 | TSHR (0.53) | KDM4EALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL29610193 | 0.70 | NAAA (0.48) | KDM4EALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL456516 | 0.69 | ALDH1A1 (0.59) | KDM4EALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL13348627 | 0.69 | KDM4E (0.66) | KDM4EALDH1A1TSHRLMNACYP1A2 | |
| SCHEMBL3264981 | 0.69 | GPR84 (0.39) | KDM4EHSD17B10TSHRKMT2AMEN1 | |
| SCHEMBL28362405 | 0.68 | TSHR (0.54) | KDM4EALDH1A1HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023938-A1 | Preparation of pyrrole-2-acetates | McNeilab, Inc. (US) | 1981-02-18 | — | — | EP | disclosed |