Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380455 | 0.90 | ADORA2B (0.54) | ADORA2BRXFP1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL11385288 | 0.87 | PDE1A (0.52) | ADORA2BSMN1; SMN2LMNA | |
| SCHEMBL11377411 | 0.82 | ADORA2B (0.59) | ADORA2BRXFP1LMNAADORA1MAPT | |
| SCHEMBL11381763 | 0.81 | ADORA2B (0.56) | ADORA2BRXFP1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11380544 | 0.80 | ADORA2B (0.59) | ADORA2BRXFP1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11374923 | 0.79 | ADORA2B (0.62) | ADORA2BRXFP1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL11382729 | 0.78 | ADORA2B (0.45) | ADORA2BRXFP1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL11378214 | 0.78 | PDE1A (0.51) | ADORA2BSMN1; SMN2LMNA | |
| Dimethylamine SCHEMBL11381767 | 0.76 | SMN1; SMN2 (0.59) | ADORA2BRXFP1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL17748272 | 0.76 | ADORA1 (0.76) | ADORA2BRXFP1MAPK1LMNAADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061753-A | Treating psoriasis with transient pro-drug forms of xanthine derivatives | INTERX RESEARCH CORPORATION (US) | 1977-12-06 | — | — | US | claimed |
| US-4275064-A | Transient pro-drug forms of xanthine derivatives and their use as topical anti-inflammatory agents | INTERX RESEARCH CORPORATION (US) | 1981-06-23 | — | — | US | disclosed |
| US-4061753-A | Treating psoriasis with transient pro-drug forms of xanthine derivatives | INTERX RESEARCH CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |