SCHEMBL11389259

SCHEMBL11389259

CN(C=O)C(=O)c1nc(Cl)c(Cl)[nH]1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11155938 0.82 MAP4K1 (0.35) HRH4
SCHEMBL11161713 0.79
SCHEMBL11154209 0.77 PDK2 (0.31)
SCHEMBL11161716 0.76 HRH4 (0.30) HRH4
SCHEMBL11166561 0.74 RIPK1 (0.33)
SCHEMBL11389233 0.74 ALDH1A1 (0.38) HRH4
SCHEMBL11283559 0.71 KDM4E (0.34)
SCHEMBL11378205 0.71 POLB (0.50)
SCHEMBL11162912 0.70 ADORA3 (0.37)
SCHEMBL11377997 0.70 TSHR (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4268681-A HERBICIDES, PLANT GROWTH REGULATORS, INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-05-19 US disclosed
US-4234722-A HERBICIDES, PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1980-11-18 US disclosed
US-4233058-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-11-11 US disclosed
US-4187100-A 4,5-Dichloro-imidazole-1-carboxylic acid aryl esters and their use as herbicides BAYER AKTIENGESELLSCHAFT (DE) 1980-02-05 US disclosed
US-4187101-A 1-Acyloxymethyl-4,5-dichloro-imidazole derivatives and their use as herbicides BAYER AKTIENGESELLESCHAFT (DE) 1980-02-05 US disclosed
US-4185991-A 4,5-Dichloro-imidazole derivatives and their use as herbicides BAYER AKTIENGESELLSCHAFT (DE) 1980-01-29 US disclosed
US-4183742-A HERBICIDES, INSECTICIDES, MITICIDES, PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1980-01-15 US disclosed
US-4178166-A HERBICIDES, INSECTICIDES, PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1979-12-11 US disclosed
US-4177055-A HERBICIDES, INSECTICIDES, MITICIDES, PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1979-12-04 US disclosed