Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 1/20 | 0.35 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20467009 | 0.84 | CYP3A4 (0.41) | LMNACYP3A4TRPM8SLC6A2SLC6A4 | |
| SCHEMBL14930912 | 0.81 | LMNA (0.39) | LMNACYP3A4TRPM8SLC6A2SLC6A4 | |
| SCHEMBL8592279 | 0.79 | AOC3 (0.36) | LMNACYP3A4SLC6A2SLC6A4TSHR | |
| SCHEMBL10989335 | 0.79 | TAAR1 (0.43) | LMNACYP3A4TP53KDM4EPER2 | |
| SCHEMBL10766412 | 0.78 | CYP3A4 (0.37) | LMNACYP3A4TRPM8SLC6A2SLC6A4 | |
| SCHEMBL20133731 | 0.78 | CYP3A4 (0.37) | LMNACYP3A4TRPM8SLC6A2SLC6A4 | |
| SCHEMBL28128935 | 0.77 | SIGMAR1 (0.50) | LMNASLC6A2SLC6A4TSHRNPSR1 | |
| SCHEMBL2124908 | 0.75 | TSHR (0.39) | LMNACYP3A4TRPM8SLC6A2SLC6A4 | |
| SCHEMBL11673976 | 0.75 | LMNA (0.36) | LMNACYP3A4TRPM8SLC6A2SLC6A4 | |
| SCHEMBL30551685 | 0.75 | KDM4E (0.38) | LMNACYP3A4SLC6A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4295853-A | EXTRACTING LIPOPEROXIDE FROM BLOOD OR SERUM, OXIDIZABLE COLOR REAGENT, COMPOUND OF MULTIVALENT METAL | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1981-10-20 | — | — | US | disclosed |
| US-3950287-A | CURING, AMINES, FREE RADICAL CATALYSTS | ASHLAND OIL, INC. (US) | 1976-04-13 | — | — | US | disclosed |