Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930912 | 0.85 | LMNA (0.39) | CYP3A4LMNATSHRNPSR1SIGMAR1 | |
| SCHEMBL20467009 | 0.81 | CYP3A4 (0.41) | CYP3A4LMNATSHRNPSR1ALDH1A1 | |
| SCHEMBL11224822 | 0.79 | KDM4E (0.38) | CYP3A4LMNATSHRALDH1A1SLC6A4 | |
| SCHEMBL30551685 | 0.79 | KDM4E (0.38) | CYP3A4LMNATSHRALDH1A1SLC6A4 | |
| SCHEMBL11389447 | 0.78 | LMNA (0.42) | CYP3A4LMNATSHRNPSR1SIGMAR1 | |
| SCHEMBL10766412 | 0.75 | CYP3A4 (0.37) | CYP3A4LMNATSHRNPSR1ALDH1A1 | |
| SCHEMBL21581184 | 0.73 | CYP3A4 (0.40) | CYP3A4LMNATSHRNPSR1SIGMAR1 | |
| SCHEMBL11673976 | 0.72 | LMNA (0.36) | CYP3A4LMNATSHRALDH1A1SLC6A2 | |
| SCHEMBL29216797 | 0.69 | LMNA (0.38) | CYP3A4LMNATSHRNPSR1SIGMAR1 | |
| SCHEMBL11034128 | 0.69 | LMNA (0.42) | CYP3A4LMNATSHRNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | CYP3A4 3827/4885LMNA 3104/4885TSHR 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.