Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513946 | 0.86 | TSHR (0.56) | TSHRHTR2AHTR2CHTR2BLMNA | |
| SCHEMBL11390990 | 0.82 | HPGD (0.36) | TSHRHTR2AHTR2CHTR2BLMNA | |
| SCHEMBL11292911 | 0.79 | PPARA (0.41) | TSHRHTR2AMAPTNPSR1CYP1A2 | |
| SCHEMBL11391260 | 0.78 | OGG1 (0.45) | MAPTKDM4EALDH1A1POLBKMT2A | |
| SCHEMBL11398917 | 0.78 | LMNA (0.39) | TSHRLMNASMN1; SMN2TDP1GAA | |
| SCHEMBL11396248 | 0.77 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2ALDH1A1TDP1NPC1 | |
| SCHEMBL11385634 | 0.77 | HPGD (0.40) | TSHRLMNAMAPTNPSR1KDM4E | |
| SCHEMBL11160254 | 0.76 | SMN1; SMN2 (0.49) | TSHRLMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL11634149 | 0.76 | TSHR (0.54) | TSHRHTR2AHTR2CHTR2BLMNA | |
| SCHEMBL11392994 | 0.76 | PPARA (0.42) | TSHRHTR2AMAPTNPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255434-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-10 | — | — | US | disclosed |