Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402166 | 0.94 | LMNA (0.44) | GPR52TRPV1ALOX5ALDH1A1CYP1A2 | |
| SCHEMBL11393634 | 0.88 | GPR52 (0.37) | GPR52TRPV1ALOX5ALDH1A1CYP1A2 | |
| SCHEMBL11394250 | 0.88 | MAPT (0.39) | GPR52ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11396435 | 0.87 | GPR52 (0.37) | GPR52ALDH1A1KMT2A | |
| SCHEMBL11395874 | 0.85 | EPHX1 (0.39) | ALOX5RAB9ALMNA | |
| SCHEMBL11398878 | 0.84 | SLC6A2 (0.37) | GPR52ALDH1A1CYP3A4LMNAKCNH3 | |
| SCHEMBL11407909 | 0.82 | HPGD (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11402070 | 0.80 | HTT (0.37) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL11395959 | 0.80 | AKT1 (0.46) | GPR52ALDH1A1CYP3A4MAPTRAB9A | |
| SCHEMBL11395451 | 0.80 | FFAR1 (0.38) | ALDH1A1CYP3A4MAPTLMNAKCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243683-A | INSECTICIDES, MITICIDES | MAY & BAKER LIMITED (GB) | 1981-01-06 | — | — | US | claimed |
| US-4243683-A | INSECTICIDES, MITICIDES | MAY & BAKER LIMITED (GB) | 1981-01-06 | — | — | US | disclosed |