Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11391703 | 0.88 | GPR52 (0.51) | GPR52TRPV1LMNAHTTCYP3A4 | |
| SCHEMBL11396435 | 0.87 | GPR52 (0.37) | GPR52PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL11402166 | 0.82 | LMNA (0.44) | GPR52TRPV1LMNACYP3A4ALDH1A1 | |
| SCHEMBL11398878 | 0.82 | SLC6A2 (0.37) | GPR52LMNAHTTPLAAT3PLAAT5 | |
| SCHEMBL11392990 | 0.81 | PPARA (0.40) | LMNACYP3A4ALDH1A1TDP1CYP1A2 | |
| SCHEMBL11395874 | 0.78 | EPHX1 (0.39) | LMNAGAAHDAC1HDAC8ALOX5 | |
| SCHEMBL11394250 | 0.76 | MAPT (0.39) | GPR52LMNACYP3A4ALDH1A1TDP1 | |
| SCHEMBL11388461 | 0.75 | PPARG (0.43) | LMNACYP3A4ALDH1A1TDP1PPARG | |
| SCHEMBL11407909 | 0.74 | HPGD (0.46) | GAAALDH1A1HDAC1HDAC2TDP1 | |
| SCHEMBL11400055 | 0.73 | POLB (0.45) | GAAALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243683-A | INSECTICIDES, MITICIDES | MAY & BAKER LIMITED (GB) | 1981-01-06 | — | — | US | claimed |
| US-4243683-A | INSECTICIDES, MITICIDES | MAY & BAKER LIMITED (GB) | 1981-01-06 | — | — | US | disclosed |