SCHEMBL113922

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL113761	1.00	BRD4 (0.56)	BRD4KDM4EL3MBTL1HTTNPC1
	SCHEMBL114752	1.00	BRD4 (0.56)	BRD4KDM4EL3MBTL1HTTNPC1
	SCHEMBL112246	0.83	KDM4E (0.59)	BRD4KDM4EL3MBTL1HTTNPC1
	SCHEMBL113628	0.83	KDM4E (0.59)	BRD4KDM4EL3MBTL1HTTNPC1
	SCHEMBL112267	0.83	KDM4E (0.59)	BRD4KDM4EL3MBTL1HTTNPC1
	SCHEMBL12119901	0.83	BRD4 (0.53)	BRD4KDM4EL3MBTL1HTTNPC1
	SCHEMBL113635	0.78	BRD4 (0.48)	BRD4KDM4EL3MBTL1HTTNPC1
	SCHEMBL113669	0.78	BRD4 (0.48)	BRD4KDM4EL3MBTL1HTTNPC1
	SCHEMBL112274	0.78	BRD4 (0.48)	BRD4KDM4EL3MBTL1HTTNPC1
	SCHEMBL10155529	0.76	KDM4E (0.64)	BRD4KDM4EL3MBTL1HTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.