Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11393334 | 0.87 | MAPT (0.62) | KMT2AMAPTTSHRHSD17B10MAPK1 | |
| SCHEMBL11394247 | 0.83 | CETP (0.62) | MAPTALDH1A1GAANPC1RAB9A | |
| SCHEMBL11396473 | 0.79 | MAPT (0.65) | MEN1KMT2AMAPTHSD17B10MAPK1 | |
| SCHEMBL14503599 | 0.79 | MEN1 (0.65) | MEN1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL16422631 | 0.77 | MEN1 (0.63) | MEN1KMT2ACYP11B2MAPTTSHR | |
| SCHEMBL10373626 | 0.77 | MAPT (0.77) | MEN1KMT2AMAPTTSHRMAPK1 | |
| SCHEMBL11385215 | 0.74 | HRH4 (0.60) | MAPTALDH1A1HTTKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11161115 | 0.73 | HRH4 (0.58) | MAPTALDH1A1HTTHTR2AKDM4E | |
| SCHEMBL17207655 | 0.72 | CYP11B2 (1.00) | MEN1KMT2ACYP11B2MAPTMAPK1 | |
| SCHEMBL11394205 | 0.72 | GAA (0.58) | MEN1KMT2AMAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258188-A | HYPOTENSIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-03-24 | — | — | US | claimed |