Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648711 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LDHAPOLBCA1CA2 | |
| SCHEMBL32668995 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LDHAPOLBCA1CA2 | |
| SCHEMBL29658757 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LDHAPOLBCA1CA2 | |
| SCHEMBL28760508 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LDHAPOLBCA1CA2 | |
| SCHEMBL27684774 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LDHAPOLBCA1CA2 | |
| SCHEMBL11400920 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LDHAPOLBCA1CA2 | |
| SCHEMBL1649908 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LDHAPOLBCA1CA2 | |
| SCHEMBL11400542 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LDHAPOLBCA1CA2 | |
| SCHEMBL8974036 | 0.78 | LDHA (0.57) | ALDH1A1LDHAPOLBCA1CA2 | |
| SCHEMBL9776046 | 0.78 | HPGD (0.46) | ALDH1A1POLBCA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4280008-A | CHEMICAL INTERMEDIATES FOR OPTICALLY ACTIVE AMINO ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |