Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776042 | 1.00 | HPGD (0.46) | HPGDSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9776124 | 0.81 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9776114 | 0.81 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL17506734 | 0.79 | CYP3A4 (0.47) | HPGDSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL11393441 | 0.78 | ALDH1A1 (0.48) | HPGDSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL11533035 | 0.77 | ALDH1A1 (0.46) | HPGDSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL11533031 | 0.77 | ALDH1A1 (0.46) | HPGDSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9775999 | 0.77 | TSHR (0.38) | HPGDSMN1; SMN2TSHRFDPSHAO1 | |
| SCHEMBL11551261 | 0.76 | KDM4E (0.42) | HPGDSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9775967 | 0.74 | MAPT (0.64) | HPGDSMN1; SMN2KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994617-A | Analgesics | JOUVEINAL S.A. (FR) | 1991-02-19 | — | — | US | disclosed |
| EP-0237366-B1 | AMINO ALCOHOLS, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS, IN PARTICULAR FOR THEREPEUTICAL USE | JOUVEINAL S.A. (FR) | 1989-04-26 | — | — | EP | disclosed |
| EP-0237366-A1 | Amino alcohols, process for their preparation and their applications, in particular for therepeutical use | JOUVEINAL S.A. (FR) | 1987-09-16 | — | — | EP | disclosed |