Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21810792 | 0.93 | DRD2 (0.53) | HTR2CDRD2DRD3DRD4 | |
| SCHEMBL28818474 | 0.85 | DRD2 (0.59) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL28818497 | 0.83 | PROKR1 (0.46) | HTR2CDRD2DRD3DRD1DRD4 | |
| SCHEMBL23009630 | 0.82 | SCD5 (0.46) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL11393853 | 0.81 | DRD2 (0.59) | HTR2CDRD2PRKDCDRD3BTK | |
| Hydrochloric Acid SCHEMBL11397089 | 0.80 | DRD2 (0.58) | HTR2CDRD2PRKDCDRD3 | |
| SCHEMBL14323106 | 0.79 | DRD2 (0.54) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL15650332 | 0.79 | DRD2 (0.53) | HTR2CDRD2DRD3DRD1DRD4 | |
| SCHEMBL11403534 | 0.78 | CNR2 (0.60) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL16457233 | 0.77 | HTR2C (0.72) | HTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259337-A | ANTIDEPRESSANTS, ANOREXIGENIC AGENTS ANTIPARKINSONIAN ACTIVITY | ROUSSEL UCLAF (FR) | 1981-03-31 | — | — | US | disclosed |