Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | USP5 | P45974 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21810792 | 0.92 | DRD2 (0.53) | DRD2HTR2CGRM2DRD4CHRM4 | |
| SCHEMBL11394435 | 0.85 | HTR2C (0.50) | DRD2HTR2CDRD4DRD1DRD5 | |
| SCHEMBL22688514 | 0.81 | P2RY14 (0.57) | DRD2HTR2CGRM2DRD4ADRA2A | |
| SCHEMBL1065758 | 0.81 | HTR2C (0.77) | DRD2HTR2CGRM2DRD4TRPV6 | |
| SCHEMBL17753658 | 0.80 | NPC1 (0.49) | GRM2DRD4CHRM4USP5 | |
| SCHEMBL6926283 | 0.80 | DRD2 (0.72) | DRD2HTR2CGRM2DRD4CHRM4 | |
| SCHEMBL20851092 | 0.80 | DRD2 (0.63) | DRD2HTR2CGRM2DRD4CHRM4 | |
| SCHEMBL5915231 | 0.80 | DRD2 (0.53) | DRD2HTR2CGRM2DRD4CHRM4 | |
| SCHEMBL1581482 | 0.78 | DRD2 (0.58) | DRD2HTR2CGRM2CHRM4USP5 | |
| SCHEMBL31484365 | 0.78 | ADRA2A (0.44) | DRD2HTR2CGRM2DRD4ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | disclosed |