Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160824 | 0.97 | DRD2 (0.56) | DRD2DRD3DRD1HTR2AKDM4E | |
| Hydrochloric Acid SCHEMBL11162051 | 0.96 | DRD2 (0.55) | DRD2DRD3DRD1HTR2AKDM4E | |
| SCHEMBL5464377 | 0.74 | DRD2 (0.70) | DRD2DRD3DRD1HTR2AKDM4E | |
| SCHEMBL4906409 | 0.73 | DRD2 (0.58) | DRD2DRD3DRD1HTR2AKDM4E | |
| Bromide SCHEMBL15528522 | 0.73 | DRD2 (0.69) | DRD2DRD3DRD1HTR2AKDM4E | |
| SCHEMBL1692381 | 0.70 | DRD2 (1.00) | DRD2DRD3DRD1HTR2AKDM4E | |
| SCHEMBL3265051 | 0.67 | DRD2 (0.72) | DRD2DRD3DRD1HTR2AKDM4E | |
| SCHEMBL30004318 | 0.67 | DRD2 (0.72) | DRD2DRD3DRD1HTR2AKDM4E | |
| SCHEMBL2554856 | 0.67 | DRD2 (0.72) | DRD2DRD3DRD1HTR2AKDM4E | |
| SCHEMBL29506709 | 0.67 | KDM4E (0.80) | DRD2DRD3DRD1HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279914-A | 1-GLAUCINE OR TETRAHYDROXYAPORPHINE, ANTICOAGULANTS | HERMANN GOTTFRIED SCHNABEL FA. (DE) | 1981-07-21 | — | — | US | disclosed |