Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11083780 | 0.84 | ALOX5 (0.49) | ALDH1A1LTA4HKMT2ANAMPTALOX5 | |
| SCHEMBL11091798 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LTA4HKMT2ANAMPTCYP3A4 | |
| SCHEMBL11094819 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LTA4HKMT2ANAMPTCYP3A4 | |
| SCHEMBL11087319 | 0.82 | KMT2A (0.52) | ALDH1A1KMT2ANAMPTCYP3A4 | |
| SCHEMBL11609561 | 0.82 | KMT2A (0.57) | ALDH1A1KMT2ANAMPTCYP3A4 | |
| SCHEMBL11394852 | 0.81 | HDAC1 (0.45) | ALDH1A1KMT2ANAMPTCYP3A4CYP2D6 | |
| SCHEMBL11088418 | 0.81 | CYP3A4 (0.47) | ALDH1A1LTA4HKMT2ANAMPTCYP3A4 | |
| SCHEMBL11093514 | 0.81 | KMT2A (0.42) | ALDH1A1LTA4HKMT2ANAMPT | |
| SCHEMBL11267493 | 0.80 | ALOX5 (0.43) | ALDH1A1LTA4HKMT2ANAMPTCYP3A4 | |
| SCHEMBL11086177 | 0.80 | LTA4H (0.54) | ALDH1A1LTA4HKMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262128-A | HAVING PROSTAGLANDIN-LIKE BIOLOGICAL PROPERTIES | BURROUGHS WELLCOME CO. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4204068-A | Nitrogen heterocycles | BURROUGHS WELLCOME CO. (US) | 1980-05-20 | — | — | US | disclosed |