Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CHRND | Q07001 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11263850 | 0.99 | CHRNA7 (0.35) | CHRNA7ALDH1A1HTR3ACHRNA1CHRNG | |
| SCHEMBL11452402 | 0.80 | USP2 (0.35) | CHRNA7ALDH1A1MEN1KMT2A | |
| SCHEMBL7362279 | 0.78 | HTR4 (0.53) | HTR3A | |
| Hydrochloric Acid SCHEMBL7359454 | 0.77 | HTR4 (0.52) | HTR3A | |
| Hydrochloric Acid SCHEMBL7355045 | 0.76 | HTR4 (0.52) | HTR3A | |
| SCHEMBL11397116 | 0.74 | HPGD (0.58) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11263860 | 0.74 | HPGD (0.57) | ALDH1A1 | |
| SCHEMBL1748557 | 0.71 | KMT2A (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7414248 | 0.70 | HTR3A (0.52) | HTR3AMEN1KMT2A | |
| SCHEMBL11262018 | 0.69 | TDP1 (0.39) | ALDH1A1HTR3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255580-A | TREATMENT OF PSYCHOLOGICAL DISORDERS | SIOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1981-03-10 | — | — | US | claimed |