Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416813 | 0.91 | HTR3A (0.52) | HTR3AMEN1KMT2AHTR4KCNH2 | |
| SCHEMBL7271062 | 0.84 | DRD2 (0.53) | HTR3AMEN1KMT2AHTR4KCNH2 | |
| SCHEMBL7270659 | 0.80 | DRD2 (0.52) | HTR3AMEN1KMT2AHTR4KCNH2 | |
| SCHEMBL7302570 | 0.79 | HTR4 (0.61) | HTR3AHTR4KCNH2 | |
| SCHEMBL7302326 | 0.79 | HTR4 (0.61) | HTR3AHTR4KCNH2 | |
| Hydrochloric Acid SCHEMBL7377307 | 0.79 | HTR4 (0.61) | HTR3AHTR4KCNH2 | |
| Hydrochloric Acid SCHEMBL7377304 | 0.79 | HTR4 (0.61) | HTR3AHTR4KCNH2 | |
| SCHEMBL8939976 | 0.78 | HTR3A (0.49) | HTR3AMEN1KMT2AHTR4KCNH2 | |
| SCHEMBL7270890 | 0.77 | HTR3A (0.48) | HTR3AMEN1KMT2AHTR4KCNH2 | |
| SCHEMBL7417950 | 0.76 | HTR3A (0.48) | HTR3AMEN1KMT2AHTR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561910-A1 | PHARMACEUTICALS | BEECHAM GROUP PLC (GB) | 1993-09-29 | — | — | EP | claimed |
| WO-1992010494-A1 | PHARMACEUTICALS | BEECHAM GROUP P.L.C. (GB) | 1992-06-25 | — | — | WO | claimed |
| WO-1992010494-A1 | PHARMACEUTICALS | BEECHAM GROUP P.L.C. (GB) | 1992-06-25 | — | — | WO | disclosed |