SCHEMBL11397147

SCHEMBL11397147

BrC(Br)=C(Br)COC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.47
HRH4 Q9H3N8 1/20 0.34
DUT P33316 3/20 0.34
ALOX15 P16050 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP2C19 P33261 3/20 0.33
CYP2C9 P11712 3/20 0.33
TSHR P16473 1/20 0.33
SLC6A1 P30531 1/20 0.33
CYP1A2 P05177 1/20 0.32
TK1 P04183 4/20 0.32
TK2 O00142 2/20 0.32
MAPK1 P28482 1/20 0.31
ELANE P08246 1/20 0.31
KCNN4 O15554 1/20 0.31
HIF1A Q16665 1/20 0.31
CYP3A4 P08684 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7057598 0.80 KIF11 (0.47) KIF11HRH4DUTALOX15ALDH1A1
SCHEMBL40498 0.75 KIF11 (0.50) KIF11ALOX15ALDH1A1CYP2C19TSHR
SCHEMBL23314251 0.75 KIF11 (0.50) KIF11HRH4DUTALOX15ALDH1A1
SCHEMBL17965751 0.73 KIF11 (0.48) KIF11HRH4DUTALOX15ALDH1A1
SCHEMBL432743 0.73 KIF11 (0.44) KIF11HRH4DUTALOX15ALDH1A1
SCHEMBL17237864 0.72 KIF11 (0.47) KIF11HRH4DUTALOX15ALDH1A1
SCHEMBL28446874 0.72 KIF11 (0.52) KIF11ALDH1A1CYP2C19CYP2C9SLC6A1
SCHEMBL9548452 0.72 KIF11 (0.47) KIF11ALOX15ALDH1A1CYP2C19SLC6A1
SCHEMBL7055637 0.72 KIF11 (0.47) KIF11HRH4DUTALOX15ALDH1A1
SCHEMBL7054160 0.72 KIF11 (0.47) KIF11DUTALOX15ALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE30497-E HALOGENATED COMPOUND, ELEMENTAL PHOSPHORUS THE DOW CHEMICAL COMPANY (US) 1981-01-27 US disclosed
US-4086192-A Olefin polymer composition having reduced flame propagation characteristics THE DOW CHEMICAL COMPANY (US) 1978-04-25 US disclosed
US-4012343-A PHOSPHORUS, HALOGENATED COMPOUND THE DOW CHEMICAL COMPANY (US) 1977-03-15 US disclosed