Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40498 | 0.83 | KIF11 (0.50) | KIF11SLC6A1CYP2C19HIF1AKCNN4 | |
| SCHEMBL17965751 | 0.82 | KIF11 (0.48) | KIF11SLC6A1CYP2C19HIF1AKCNN4 | |
| SCHEMBL7054160 | 0.80 | KIF11 (0.47) | KIF11SLC6A1CYP2C19HIF1AKCNN4 | |
| SCHEMBL9548452 | 0.80 | KIF11 (0.47) | KIF11SLC6A1CYP2C19HIF1AKCNN4 | |
| SCHEMBL11397147 | 0.80 | KIF11 (0.47) | KIF11SLC6A1CYP2C19HIF1AKCNN4 | |
| SCHEMBL7055637 | 0.80 | KIF11 (0.47) | KIF11SLC6A1CYP2C19HIF1AKCNN4 | |
| SCHEMBL17237864 | 0.80 | KIF11 (0.47) | KIF11SLC6A1CYP2C19HIF1AKCNN4 | |
| SCHEMBL28446874 | 0.80 | KIF11 (0.52) | KIF11SLC6A1CYP2C19HIF1AKCNN4 | |
| SCHEMBL10335929 | 0.78 | KIF11 (0.46) | KIF11SLC6A1CYP2C19HIF1AKCNN4 | |
| SCHEMBL9292102 | 0.78 | KIF11 (0.46) | KIF11SLC6A1CYP2C19HIF1AKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181742-A1 | Process for the preparation of pregnane derivatives | KURARAY CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1325928-A1 | PROCESS FOR THE PREPARATION OF PREGNANE DERIVATIVES | Kuraray Co., Ltd. (JP) | 2003-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181742-A1 | Process for the preparation of pregnane derivatives | CYP21A2, CYP11B2, CYP17A1 | KIF11 2036/4885SLC6A1 845/4885CYP2C19 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.