SCHEMBL17965751

SCHEMBL17965751

[O]C(=O)COC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.48
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 2/20 0.39
KCNN4 O15554 1/20 0.39
SLC6A1 P30531 1/20 0.39
CYP1A2 P05177 1/20 0.39
ALOX15 P16050 3/20 0.38
CYP2C9 P11712 2/20 0.37
CYP3A4 P08684 1/20 0.37
KCNH2 Q12809 1/20 0.37
ELANE P08246 1/20 0.37
KMT2A Q03164 2/20 0.36
DUT P33316 2/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CES1 P23141 1/20 0.36
HDAC6 Q9UBN7 2/20 0.36
MEN1 O00255 1/20 0.36
HRH4 Q9H3N8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40498 0.85 KIF11 (0.50) KIF11CYP2C19HIF1AKCNN4SLC6A1
SCHEMBL7055637 0.82 KIF11 (0.47) KIF11CYP2C19HIF1AKCNN4SLC6A1
SCHEMBL28446874 0.82 KIF11 (0.52) KIF11CYP2C19HIF1AKCNN4SLC6A1
SCHEMBL7057598 0.82 KIF11 (0.47) KIF11CYP2C19HIF1AKCNN4SLC6A1
SCHEMBL9548452 0.82 KIF11 (0.47) KIF11CYP2C19HIF1AKCNN4SLC6A1
SCHEMBL7054160 0.82 KIF11 (0.47) KIF11CYP2C19HIF1AKCNN4SLC6A1
SCHEMBL17237864 0.82 KIF11 (0.47) KIF11CYP2C19HIF1AKCNN4SLC6A1
SCHEMBL10335929 0.80 KIF11 (0.46) KIF11CYP2C19HIF1AKCNN4SLC6A1
SCHEMBL9292102 0.80 KIF11 (0.46) KIF11CYP2C19HIF1AKCNN4SLC6A1
SCHEMBL889518 0.79 HSD11B1 (0.47) KIF11CYP2C19HIF1AKCNN4SLC6A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105859529-B Method for producing asymmetric conjugated diyne compound and method for producing Z, Z-conjugated diene compound using the same 信越化学工业株式会社 2020-10-16 CN disclosed
EP-3053906-B1 METHOD FOR PRODUCING ASYMMETRIC CONJUGATED DIYNE COMPOUND AND METHOD FOR PRODUCING Z,Z-CONJUGATED DIENE COMPOUND USING THE SAME SHINETSU CHEMICAL CO (JP) 2017-12-27 EP disclosed
US-9845304-B2 Method for producing asymmetric conjugated diyne compound and method for producing Z,Z-conjugated diene compound using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-19 US disclosed
US-20160229829-A1 Method for Producing Asymmetric Conjugated Diyne Compound and Method for Producing Z,Z-Conjugated Diene Compound Using the Same SHIN-ETSU CHEMICAL CO., LTD (JP) 2016-08-11 US disclosed
EP-3053906-A1 METHOD FOR PRODUCING ASYMMETRIC CONJUGATED DIYNE COMPOUND AND METHOD FOR PRODUCING Z,Z-CONJUGATED DIENE COMPOUND USING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2016-08-10 EP disclosed