Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3507651 | 0.70 | CSNK2A2 (0.43) | ALDH1A1MAPTKDM4ECSNK2A2CSNK2B | |
| SCHEMBL2032749 | 0.70 | CSNK2A2 (0.43) | ALDH1A1MAPTKDM4ECSNK2A2CSNK2B | |
| SCHEMBL150034 | 0.68 | KMT2A (0.53) | ALDH1A1MAPTKDM4EKMT2AUSP5 | |
| SCHEMBL18180382 | 0.68 | KMT2A (0.45) | KDM4EKMT2AUSP5GAACASP1 | |
| SCHEMBL28937167 | 0.66 | ALDH1A1 (0.43) | ALDH1A1PTGDR2MAPTKDM4ECSNK2A2 | |
| SCHEMBL11543182 | 0.65 | ALDH1A1 (0.43) | ALDH1A1PTGDR2MAPTKDM4ECSNK2A2 | |
| SCHEMBL7336986 | 0.65 | KDM4E (0.45) | ALDH1A1MAPTKDM4ECSNK2A2CSNK2B | |
| SCHEMBL994533 | 0.64 | KMT2A (0.53) | ALDH1A1KDM4ECSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6526383 | 0.62 | CSNK2A2 (0.37) | ALDH1A1MAPTKDM4ECSNK2A2CSNK2B | |
| SCHEMBL27524563 | 0.62 | CSNK2A2 (0.37) | ALDH1A1MAPTKDM4ECSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4278685-A | DICHLORO-1-PYRROLYLALKANAMIDES, ANTIULCER AGENTS, ANTISECRETORY AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1981-07-14 | — | — | US | disclosed |
| US-4140793-A | HYPOGLYCEMIC AGENTS, ANTIULCER AGENTS | JOHN WYETH & BROTHER, LTD. (GB) | 1979-02-20 | — | — | US | disclosed |