Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308075 | 0.87 | POLB (0.37) | POLBALDH1A1GAAMAPK1TDP1 | |
| SCHEMBL11474652 | 0.81 | CES2 (0.34) | ALDH1A1GAATDP1HTTCES2 | |
| SCHEMBL11399489 | 0.81 | MAPK1 (0.31) | MAPK1MAPT | |
| SCHEMBL11406520 | 0.79 | ESR2 (0.36) | ALDH1A1HDAC11SLC6A3MAPT | |
| SCHEMBL11394882 | 0.79 | MAPT (0.40) | KDM4EALDH1A1GAACES2CES1 | |
| SCHEMBL11311893 | 0.78 | CHRM2 (0.35) | POLBKDM4EALDH1A1MAPK1CHRM2 | |
| SCHEMBL11303200 | 0.77 | HTT (0.39) | POLBKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL11303199 | 0.77 | HTT (0.39) | POLBKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL9518851 | 0.73 | SMN1; SMN2 (0.38) | POLBTDP1MAPTSMN1; SMN2 | |
| SCHEMBL3286887 | 0.69 | MAOB (0.44) | KDM4EALDH1A1HTTCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264606-A | Insecticidal and acaricidal phenylcyclo-propane carboxylic acid derivatives and insecticidal and acaricidal compositions thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1981-04-28 | — | — | US | disclosed |
| US-4215138-A | Insecticidal compounds of phenylcyclopropane carboxylic acid esters | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1980-07-29 | — | — | US | disclosed |