Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11395710 | 0.88 | MAPK1 (0.40) | ALDH1A1LMNAMEN1KMT2ASLC6A4 | |
| SCHEMBL11406520 | 0.84 | ESR2 (0.36) | ALDH1A1CYP2C9LMNASLC6A3 | |
| SCHEMBL11394882 | 0.84 | MAPT (0.40) | CES2CES1ALDH1A1LMNAMEN1 | |
| SCHEMBL11308075 | 0.83 | POLB (0.37) | ALDH1A1CYP1A2CYP2C19LMNAMEN1 | |
| SCHEMBL11311893 | 0.83 | CHRM2 (0.35) | ALDH1A1CYP2C9LMNAMEN1KMT2A | |
| SCHEMBL11399489 | 0.83 | MAPK1 (0.31) | — | |
| SCHEMBL11397455 | 0.81 | POLB (0.38) | CES2CES1ALDH1A1CYP3A4SLC6A3 | |
| SCHEMBL11304869 | 0.78 | TSHR (0.40) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11474646 | 0.74 | SLC9A1 (0.41) | CES2CES1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15977340 | 0.69 | SLC9A1 (0.44) | CES2CES1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4215138-A | Insecticidal compounds of phenylcyclopropane carboxylic acid esters | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1980-07-29 | — | — | US | disclosed |