SCHEMBL11399489

SCHEMBL11399489

CC1(C)C(OC(=O)Cl)C1c1ccc([Si](C)(C)C)cc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11395710 0.84 MAPK1 (0.40) MAPK1MAPT
SCHEMBL11474652 0.83 CES2 (0.34)
SCHEMBL11397455 0.81 POLB (0.38) MAPK1MAPT
SCHEMBL11394882 0.80 MAPT (0.40) MAPT
SCHEMBL11406520 0.80 ESR2 (0.36) MAPT
SCHEMBL11308075 0.79 POLB (0.37) MAPK1MAPT
SCHEMBL11311893 0.79 CHRM2 (0.35) MAPK1
SCHEMBL11399486 0.76 SLC9A1 (0.39) MAPK1MAPT
SCHEMBL11304869 0.74 TSHR (0.40) MAPT
SCHEMBL9518851 0.65 SMN1; SMN2 (0.38) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4264606-A Insecticidal and acaricidal phenylcyclo-propane carboxylic acid derivatives and insecticidal and acaricidal compositions thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1981-04-28 US disclosed