Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399104 | 0.85 | VHL (0.43) | EPHX2RAB9ANPC1TDP1HPGD | |
| SCHEMBL11392506 | 0.84 | EPHX2 (0.37) | EPHX2RAB9ANPC1SLC5A7HPGD | |
| SCHEMBL11394538 | 0.78 | EPHX2 (0.42) | EPHX2RAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL965297 | 0.69 | FBP1 (0.34) | — | |
| SCHEMBL965302 | 0.68 | — | — | |
| SCHEMBL4903448 | 0.67 | CYP19A1 (0.41) | RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL6787893 | 0.67 | FDPS (0.35) | — | |
| SCHEMBL5725308 | 0.67 | CDK2 (0.38) | — | |
| SCHEMBL9285410 | 0.66 | — | — | |
| SCHEMBL1407856 | 0.66 | TRPA1 (0.42) | HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251539-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-02-17 | — | — | US | disclosed |