Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2883320 | 0.85 | MAPT (0.49) | MAPTGAAVCAM1HTTLMNA | |
| SCHEMBL11396073 | 0.83 | FBP1 (0.47) | FBP1MAPTGAALMNAMEN1 | |
| SCHEMBL11390793 | 0.80 | FBP1 (0.44) | FBP1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11388406 | 0.79 | FBP1 (0.50) | FBP1MAPTGAAVCAM1LMNA | |
| SCHEMBL11543240 | 0.79 | MAPT (0.43) | MAPTGAAVCAM1HTTLMNA | |
| SCHEMBL21437398 | 0.79 | MAPT (0.43) | MAPTGAAVCAM1HTTLMNA | |
| SCHEMBL11397185 | 0.78 | CA1 (0.42) | FBP1LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL2879281 | 0.72 | MAPT (0.48) | MAPTGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL11511421 | 0.70 | ALDH1A1 (0.43) | MAPTGAAVCAM1HTTLMNA | |
| SCHEMBL11549637 | 0.68 | KDM4E (0.50) | MAPTGAALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288449-A | DIURETICS | BASF AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | disclosed |