Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11157459 | 0.90 | CISD1 (0.39) | CA1CA2HDAC8HDAC1HDAC6 | |
| SCHEMBL11390793 | 0.84 | FBP1 (0.44) | FBP1HDAC8HDAC1HDAC6PABPC1 | |
| SCHEMBL11396073 | 0.81 | FBP1 (0.47) | FBP1PABPC1EIF4HKDM4EALDH1A1 | |
| SCHEMBL21436509 | 0.79 | CA1 (0.39) | CA1CA2HDAC8HDAC1HDAC6 | |
| SCHEMBL21436508 | 0.79 | CA1 (0.39) | CA1CA2HDAC8HDAC1HDAC6 | |
| SCHEMBL11397629 | 0.78 | FBP1 (0.46) | FBP1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11788977 | 0.76 | CISD1 (0.53) | CA1CA2HIF1AKDM4EALDH1A1 | |
| SCHEMBL11787976 | 0.75 | CA2 (0.43) | CA1CA2HIF1AKDM4EALDH1A1 | |
| SCHEMBL11788774 | 0.73 | CA2 (0.46) | CA1CA2HIF1AKDM4EALDH1A1 | |
| SCHEMBL11789999 | 0.72 | CA2 (0.45) | CA1CA2HIF1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288449-A | DIURETICS | BASF AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | disclosed |