Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | EPOR | P19235 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426521 | 0.86 | LTA4H (0.51) | TLR4TLR2ALOX5PTGS1PTGS2 | |
| SCHEMBL9130816 | 0.84 | ALOX5 (0.59) | TLR4TLR2ALOX5PTGS1PTGS2 | |
| SCHEMBL9130834 | 0.84 | ALOX5 (0.59) | TLR4TLR2ALOX5PTGS1PTGS2 | |
| SCHEMBL27693342 | 0.83 | EPOR (0.50) | TLR4TLR2ALOX5PTGS1PTGS2 | |
| SCHEMBL11193479 | 0.81 | TLR4 (0.47) | TLR4TLR2ALOX5PTGS1PTGS2 | |
| SCHEMBL16619043 | 0.80 | CHRM5 (0.60) | TDP1 | |
| SCHEMBL29484309 | 0.80 | MAOB (0.61) | TLR4TLR2ALOX5PTGS1PTGS2 | |
| SCHEMBL98478 | 0.80 | MAOB (0.61) | TLR4TLR2ALOX5PTGS1PTGS2 | |
| SCHEMBL11482497 | 0.80 | MAOB (0.61) | TLR4TLR2ALOX5PTGS1PTGS2 | |
| SCHEMBL1218847 | 0.80 | TLR4 (0.53) | TLR4TLR2ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288387-A | REACTION OF A HALOGENOPENTENE OR HEXENE WITH A DIAZOACETIC ESTER IN THE PRESENCE OF CATALYST WHICH IS METALLIC COPPER, A COPPER SALT, A RHODIUM SALT, OR A TRANSITION METAL COMPLEX OF A CHIRAL SCHIFF BASE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-09-08 | — | — | US | claimed |
| CN-1148383-A | Heterocyclylamino-and heterocyclyloxy-cycloalkyl derivatives, their preparation and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-04-23 | — | — | CN | disclosed |
| CN-86106825-A | Propylene oxide and epithio propane derivative with pesticidal | — | 1987-05-13 | — | — | CN | disclosed |