Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11396529 | 0.82 | ADAM17 (0.46) | MAPTLMNAALDH1A1KMT2ANPSR1 | |
| SCHEMBL6785391 | 0.80 | MAPT (0.49) | MAPTTDP1LMNAALDH1A1KMT2A | |
| SCHEMBL11394906 | 0.80 | ALDH1A1 (0.42) | MAPTLMNAALDH1A1KMT2ANPSR1 | |
| SCHEMBL11407319 | 0.79 | LMNA (0.40) | TDP1LMNAALDH1A1KMT2ANPSR1 | |
| SCHEMBL11453268 | 0.76 | HSD17B10 (0.47) | MAPTLMNAALDH1A1KMT2ANPSR1 | |
| SCHEMBL11402195 | 0.74 | EPHX1 (0.45) | LMNAALDH1A1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL6787275 | 0.72 | ADAM17 (0.62) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL11402217 | 0.71 | ATM (0.41) | ALDH1A1KMT2ANPSR1SMN1; SMN2AKR1C3 | |
| SCHEMBL958232 | 0.71 | CA1 (0.48) | MAPTTDP1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL30365712 | 0.71 | CA1 (0.48) | MAPTTDP1ALDH1A1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282245-A | ANTIINFLAMMATORY | NIPPON CHEMIPHAR CO., LTD. (JP) | 1981-08-04 | — | — | US | disclosed |